Table 3.
Variable | T1 (<3.49) | T2 (3.12–4.56) | T3 (>4.56) | P |
---|---|---|---|---|
Age (year) | 52.7 ± 7.3 | 54.1 ± 8.2 | 53.5 ± 7.1 | 0.199 |
Men, n (%) | 101 (49.8) | 95 (47.0) | 108 (54.0) | 0.371 |
BMI (kg/m2) | 23.0 ± 2.4ab | 24.4 ± 2.4ac | 25.7 ± 3.4bc | < 0.001 |
HbA1c (%) | 9.0 ± 1.1 | 8.9 ± 1.0 | 9.1 ± 1.1 | 0.247 |
WC (cm) | 82.5 ± 5.1ab | 85.5 ± 5.8ac | 89.0 ± 7.9bc | < 0.001 |
TG (mmol/L) | 1.51 ± 0.87ab | 1.94 ± 1.02ac | 2.99 ± 1.67bc | < 0.001 |
HDL-c (mmol/L) | 1.25 ± 0.23ab | 1.10 ± 0.20ac | 0.96 ± 0.23bc | < 0.001 |
LDL-c (mmol/L) | 3.46 ± 0.91 | 3.48 ± 0.88 | 3.49 ± 0.93 | 0.965 |
ApoA1 (g/L) | 1.19 ± 0.20ab | 1.04 ± 0.13ac | 0.86 ± 0.16bc | < 0.001 |
Monocyte (109/L) | 0.33 ± 0.06ab | 0.42 ± 0.06ac | 0.50 ± 0.10bc | < 0.001 |
UA (µmol/L) | 318.5 ± 70.3ab | 356.0 ± 74.1ac | 384.1 ± 96.9bc | < 0.001 |
Creatinine (µmol/L) | 71.8 ± 13.3 | 70.1 ± 13.1 | 69.6 ± 13.1 | 0.176 |
ALT (IU/L) | 34.7 ± 8.8 | 35.6 ± 8.9 | 34.6 ± 9.4 | 0.520 |
SBP (mmHg) | 123.5 ± 14.2ab | 132.7 ± 13.1ac | 143.2 ± 14.8bc | < 0.001 |
DBP (mmHg) | 76.0 ± 9.9ab | 81.0 ± 6.9ac | 86.6 ± 9.4bc | < 0.001 |
Insulin (mU/ml) | 19.8 ± 8.9ab | 26.1 ± 8.7ac | 33.8 ± 9.9bc | < 0.001 |
HOMA-IR | 8.2 ± 4.9ab | 10.9 ± 5.3ac | 14.0 ± 6.5bc | < 0.001 |
hs-CRP (mg/L) | 2.8 ± 0.9 | 3.0 ± 1.0 | 3.0 ± 0.9 | 0.255 |
Hypertension, n (%) | 34 (16.7)ab | 67 (33.2)ac | 114 (57.0)bc | < 0.001 |
Smoking, n (%) | 72 (35.4) | 71 (35.1) | 75 (37.2) | 0.777 |
Drinking, n (%) | 77 (37.9) | 72 (35.6) | 75 (37.2) | 0.880 |
MHR (108/mmol) | 2.73 ± 0.82ab | 3.93 ± 0.93ac | 5.42 ± 1.53bc | < 0.001 |
MetS, n (%) | 53 (26.1)ab | 128 (63.4)ac | 183 (91.5)bc | < 0.001 |
BMI, body mass index; UA, uric acid. TG, triglyceride. HDL-c, high-density lipoprotein cholesterol. LDL-c, low-density lipoprotein cholesterol. ApoA1, apolipoprotein A1.SBP, systolic blood pressure. DBP, diastolic blood pressure. HOMR-IR, homeostasis model assessment insulin resistance. hs-CRP, high-sensitivity C-reactive protein. MHR, monocyte–to–HDL-c ratio. MAR, monocyte-to-ApoA1 ratio. aP < 0.05: T1 vs. T2. bP < 0.05: T1 vs. T3. cP < 0.05: T2 vs. T3.