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. 2022 Jul 14;13:935776. doi: 10.3389/fendo.2022.935776

Table 3.

Clinical and laboratory characteristics of participants based on tertiles of MAR (108/g).

Variable T1 (<3.49) T2 (3.12–4.56) T3 (>4.56) P
Age (year) 52.7 ± 7.3 54.1 ± 8.2 53.5 ± 7.1 0.199
Men, n (%) 101 (49.8) 95 (47.0) 108 (54.0) 0.371
BMI (kg/m2) 23.0 ± 2.4ab 24.4 ± 2.4ac 25.7 ± 3.4bc < 0.001
HbA1c (%) 9.0 ± 1.1 8.9 ± 1.0 9.1 ± 1.1 0.247
WC (cm) 82.5 ± 5.1ab 85.5 ± 5.8ac 89.0 ± 7.9bc < 0.001
TG (mmol/L) 1.51 ± 0.87ab 1.94 ± 1.02ac 2.99 ± 1.67bc < 0.001
HDL-c (mmol/L) 1.25 ± 0.23ab 1.10 ± 0.20ac 0.96 ± 0.23bc < 0.001
LDL-c (mmol/L) 3.46 ± 0.91 3.48 ± 0.88 3.49 ± 0.93 0.965
ApoA1 (g/L) 1.19 ± 0.20ab 1.04 ± 0.13ac 0.86 ± 0.16bc < 0.001
Monocyte (109/L) 0.33 ± 0.06ab 0.42 ± 0.06ac 0.50 ± 0.10bc < 0.001
UA (µmol/L) 318.5 ± 70.3ab 356.0 ± 74.1ac 384.1 ± 96.9bc < 0.001
Creatinine (µmol/L) 71.8 ± 13.3 70.1 ± 13.1 69.6 ± 13.1 0.176
ALT (IU/L) 34.7 ± 8.8 35.6 ± 8.9 34.6 ± 9.4 0.520
SBP (mmHg) 123.5 ± 14.2ab 132.7 ± 13.1ac 143.2 ± 14.8bc < 0.001
DBP (mmHg) 76.0 ± 9.9ab 81.0 ± 6.9ac 86.6 ± 9.4bc < 0.001
Insulin (mU/ml) 19.8 ± 8.9ab 26.1 ± 8.7ac 33.8 ± 9.9bc < 0.001
HOMA-IR 8.2 ± 4.9ab 10.9 ± 5.3ac 14.0 ± 6.5bc < 0.001
hs-CRP (mg/L) 2.8 ± 0.9 3.0 ± 1.0 3.0 ± 0.9 0.255
Hypertension, n (%) 34 (16.7)ab 67 (33.2)ac 114 (57.0)bc < 0.001
Smoking, n (%) 72 (35.4) 71 (35.1) 75 (37.2) 0.777
Drinking, n (%) 77 (37.9) 72 (35.6) 75 (37.2) 0.880
MHR (108/mmol) 2.73 ± 0.82ab 3.93 ± 0.93ac 5.42 ± 1.53bc < 0.001
MetS, n (%) 53 (26.1)ab 128 (63.4)ac 183 (91.5)bc < 0.001

BMI, body mass index; UA, uric acid. TG, triglyceride. HDL-c, high-density lipoprotein cholesterol. LDL-c, low-density lipoprotein cholesterol. ApoA1, apolipoprotein A1.SBP, systolic blood pressure. DBP, diastolic blood pressure. HOMR-IR, homeostasis model assessment insulin resistance. hs-CRP, high-sensitivity C-reactive protein. MHR, monocyte–to–HDL-c ratio. MAR, monocyte-to-ApoA1 ratio. aP < 0.05: T1 vs. T2. bP < 0.05: T1 vs. T3. cP < 0.05: T2 vs. T3.