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. 2022 Jul 28;20:238. doi: 10.1186/s12916-022-02435-9

Table 5.

Independent association of NPR-A after weight loss and male sex with an increase of HOMA-IR at month 48 (ΔHOMA-IRT0T48). Stepwise multiple linear regression analysis was adjusted for the treatment group, age, sex, HOMA-IR after weight loss, and ΔBMIT0T48. Male sex was defined as 1 and female sex was defined as 2

Predictors Coefficients Standard error Standardized β R2
Adipose NPR-A mRNA −0.001 3.5×10-4 −0.422* 0.361**
Sex −1.669 0.650 −0.438*

NPR natriuretic receptor

*p<0.05

**p<0.01