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. 2022 Jul 22;14(15):3008. doi: 10.3390/nu14153008

Table 3.

Neonatal characteristics are stratified by maternal vitamin D oral supplementation during pregnancy.

No Supplementation (n = 59) Low Dose
(n = 63)
High Dose (n = 76) p-Value *
Neonatal characteristics
Gender (male) 33 (55.9%) 32 (50.8%) 36 (47.4%) 0.613
Abnormal APGAR score 5 (8.5%) 4 (6.3%) 4 (5.3%) 0.753
Birth weight *** (grams), mean ± SD 2731 ± 552 2880 ± 594 2926 ± 518 0.117
Conceived by vitro fertilization 1 (1.7%) 0 (0.0%) 1 (1.3%) 0.609
Delivered by C-section 28 (47.5%) 33 (52.4%) 30 (39.5%) 0.303
Infection after membrane rupture 5 (8.5%) 7 (11.1%) 7 (9.2%) 0.875
Congenital abnormalities 2 (3.4%) 2 (3.2%) 1 (1.3%) 0.691
Prematurity 8 (13.6%) 3 (4.8%) 2 (2.6%) 0.030
NICU admission 2 (3.4%) 1 (1.6%) 1 (1.3%) 0.667
Resuscitation 4 (6.8%) 2 (3.2%) 4 (5.3%) 0.657
Days of hospitalization ** 4 (3) 4 (2) 3 (2) 0.492
Therapy
Surfactant 5 (8.5%) 2 (3.2%) 2 (2.6%) 0.221
Steroids 6 (10.2%) 4 (6.3%) 4 (5.3%) 0.524
Antibiotics 18 (30.5%) 12 (19.0%) 10 (13.2%) 0.043

* Chi-square or Fisher’s exact test; ** Data represented as median [IQR]; *** In correlation with gestational age; APGAR—Appearance, Pulse, Grimace, Activity, Respiration; NICU—Neonatal Intensive Care Unit.