Table 4.
Patient records at 32 weeks and 36 weeks of gestation.
| No Supplementation (n = 59) |
Low Dose (n = 63) | High Dose (n = 76) |
p-Value * | |
|---|---|---|---|---|
| At 32 weeks | ||||
| Low vitamin D (<30 ng/mL) | 0.027 | |||
| Insufficient < 20 ng/mL (n = 25) | 12 (20.3%) | 8 (12.7%) | 5 (6.6%) | |
| Vitamin D deficiency 20–30 ng/mL (n = 37) | 15 (25.4%) | 12 (19.0%) | 10 (13.2%) | |
| Normal serum vitamin D >30 ng/mL (n = 136) | 32 (54.2%) | 43 (68.3%) | 61 (80.3%) | |
| Hypertension | 0.049 | |||
| Hypertensive | 12 (20.3%) | 7 (11.1%) | 5 (6.6%) | |
| Non-hypertensive | 47 (79.7%) | 56 (88.9%) | 71 (93.4%) | |
| Serum vitamin D, ng/mL (mean ± SD) | 23.9 ± 7.3 | 28.4 ± 8.0 | 33.6 ± 7.1 | <0.001 |
| Systolic blood pressure (mean ± SD) | 139.4 ± 33.1 | 130.2 ± 26.6 | 127.4 ± 22.5 | 0.036 |
| Dyastolic blood pressure (mean ± SD) | 85.2 ± 14.6 | 80.4 ± 11.6 | 79.1 ± 10.2 | 0.012 |
| At 36 weeks | ||||
| Vitamin D deficiency (<30) | 0.006 | |||
| Insufficient < 20 ng/mL (n = 25) | 14 (23.7%) | 7 (11.1%) | 4 (5.3%) | |
| Vitamin Ddeficiency 20–30 g/mL (n = 47) | 17 (28.8%) | 15 (23.8%) | 15 (19.7%) | |
| Normal serum vitamin D >30 ng/mL (n = 126) | 28 (47.5%) | 41 (65.1%) | 57 (75.0%) | |
| Hypertension | 0.002 | |||
| Hypertensive | 15 (25.4%) | 7 (11.1%) | 4 (5.3%) | |
| Non-hypertensive | 10 (74.6%) | 22 (88.9%) | 20 (94.7%) | |
| Serum vitamin D, ng/mL (mean ± SD) | 22.5 ± 8.1 | 29.1 ± 7.7 | 35.6 ± 8.3 | <0.001 |
| Systolic blood pressure (mean ± SD) | 141.4 ± 38.9 | 129.4 ± 30.5 | 127.3 ± 28.7 | 0.034 |
| Dyastolic blood pressure (mean ± SD) | 86.4 ± 15.9 | 81.2 ± 10.6 | 80.5 ± 9.4 | 0.012 |
| Preeclampsia | 11 (18.6%) | 6 (9.5%) | 4 (5.3%) | 0.041 |
* Chi-square or Fisher’s exact test; Data represented as mean ± SD; SD—Standard Deviation.