Table 1.

Molecular characterization of the glioma cell lines by combining our experiments and literature.

Gene	Cell line
	U87MG	LNZ308	LN229
IDH1	Mutant (R132H)	WT	WT
p53	WT/WT	intragenic deletion loss by translocation	Codon 98 CCT(Pro)→CTT(Lys)
ATRX	Mutant	Mutant	Mutant
PTEN	splice (del. exon 3) in frame deletion	splice (del. exon 6) frameshift	WT
p16	del	WT	del
p14ARF	del	WT	del
Integrated Dx	IDH-mutant astrocytoma, Gr 4	IDH-wildtype glioblastoma, Gr 4	IDH-wildtype glioblastoma, Gr 4