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Cocoa modulated total ROS/RNS productions in senescence auditory cells. ROS/RNS were measured in HEI-OC1, OC-k3, and SV-k1 cells. Experimental groups: CTR group (0, 0.5 and 5 μg/mL of CPE for 20 h) and H2O2 group (induced cellular senescence with 100 μM for 1 h in all groups: 0, 0.5 and 5 μg/mL of CPE for 20 h). The diagrams represent the mean ± SD of relative fluorescent units (RFU). * p < 0.05 vs. CTR group; # p < 0.05 vs. H2O2 group (n = 4).
