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. 2022 Jul 28;8:51. doi: 10.1186/s40942-022-00401-4

Table 3.

The demographics and baseline characteristics of the patients

Characteristics Brolucizumab N = 56 Aflibercept N = 58 P value
Age, years
Mean ± SD 72.05 ± 11.03 70.17 ± 9.02 0.32
Median 72.00 70.5
Min, max 51.00, 91.00 54.00, 91.00
Sex, n (%) 0.17
Male 37 (66.1) 30 (51.7)
Female 19 (33.9) 28 (48.3)
LogMAR BCVA
Mean ± SD 0.84 ± 0.32 0.87 ± 0.27 0.63
Min, max 0.28, 1.42 0.26, 1.30
CMT (µm)
Mean ± SD 355 ± 89.7 365.5 ± 55.78 0.46
Min, max 211.00, 598.00 265.00, 566.00
Presence of IRF n (%) 46 (82.1) 44 (75.9) 0.55
Presence of SRF n (%) 46 (82.1) 48 (82.8)  > 0.99
Presence of SHRM n (%) 24 (42.9) 31 (53.4) 0.35

Data presented as mean ± standard deviation or n (%)

BCVA Best corrected visual acuity, CMT Central macular thickness, IRF intraretinal fluid, SRF subretinal fluid, SHRM subretinal hyper-reflective material, SD standard deviation

*p-value < 0.05 for the t-test considered significant (none of the t-test found significance)

#p-values < 0.05 for the chi-square test considered for significant correlation (none of the chi-square test found correlation)