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. 2022 Jul 27;5(7):e2223080. doi: 10.1001/jamanetworkopen.2022.23080

Table 2. Association of Patient Characteristics with LVAD Usea.

Variables Marginal effect size (95% CI)
Model 1 Model 2 Model 3 Model 4 Model 5 Model 6 Model 7
Black race (vs White) –0.017 (–0.039 to 0.005) –0.022 (–0.041 to –0.003) –0.036 (–0.057 to –0.015) –0.043 (–0.065 to –0.022) –0.045 (–0.072 to –0.018) –0.030 (–0.058 to –0.002) –0.030 (–0.058 to –0.002)
Female (vs male) –0.125 (–0.146 to –0.104) –0.089 (–0.108 to –0.070) –0.090 (–0.109 to –0.071) –0.090 (–0.109 to –0.071) –0.079 (–0.102 to –0.056) –0.079 (–0.102 to –0.056) –0.079 (–0.102 to –0.056)
LVAD propensity NA 0.965 (0.941 to 0.989) 0.962 (0.938 to 0.986) 0.960 (0.936 to 0.984) 0.956 (0.926 to 0.986) 0.953 (0.923 to 0.983) 0.954 (0.924 to 0.984)
Age, per year NA NA –0.001 (–0.002 to 0.0003) –0.001 (–0.0013 to 0.0001) –0.002 (–0.003 to –0.001) –0.002 (–0.003 to –0.001) –0.002 (–0.003 to –0.001)
Distance to LVAD Hospital, per 10 miles NA NA NA –0.002 (–0.003 to –0.001) –0.003 (–0.004 to –0.002) –0.003 (–0.004 to –0.002) –0.003 (–0.004 to –0.002)
Low-income subsidy NA NA NA NA –0.036 (–0.060 to –0.012) –0.029 (–0.053 to –0.005) –0.030 (–0.054 to –0.005)
Social deprivation index NA NA NA NA NA –0.067 (–0.105 to –0.029) –0.068 (–0.106 to –0.030)
Observations 12 310 12 310 12 310 12 310 7711 7710 7710
Year indicators Yes Yes Yes Yes Yes Yes Yes
Neighborhood RE No No No No No No Yes
Part D enrollees only No No No No Yes Yes Yes

Abbreviations: LVAD, left ventricular assist device; NA, not applicable; RE, random effect.

a

Model 1 was conditional on age, sex, interactions of age and sex, and year indicators. After adjusting for expected LVAD use based on patient characteristics (Model 2), incorporating interactions with patient age (Model 3), distance to LVAD centers (Model 4), individual poverty (Model 5), and neighborhood-level social deprivation (Model 6), Black race and female sex were associated with a –3.0 (95% CI, –5.8 to –0.2) and –7.9 (95% CI, –10.2 to –5.6) percentage points decrease use of LVAD. These associations were consistent when neighborhood included as a random effect (Model 7).