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. 2022 Jul 28;22:653. doi: 10.1186/s12879-022-07634-6

Table 3.

Risk factors for malaria infection and severe malaria (2016–2018)

Descriptions Malaria cases
(n = 2402)
No infection
(n = 15,659)
COR (95%CI) AOR (95%CI) Severe cases
(n = 59)
Non–severe cases
(n = 2343)
COR (95%CI) AOR (95%CI)
n (%) n (%) n (%) n (%)
Age (years)
 <5 255 (10.6) 3371 (21.5) 1* 1 18 (30.6) 237 (10.1) 4.53 (2.25–9.12) 4.31 (2.12–8.77)
 5–14 549 (22.9) 3980 (25.4) 1.82 (1.56–2.13) 1.81 (1.55–2.12) 10 (16.9) 539 (23.0) 1.11 (0.49–2.48) 0.63 (0.17–2.37)
 15–24 689 (28.7) 3187 (20.4) 2.86 (2.46–3.33) 2.82 (2.42–3.28) 16 (27.1) 673 (28.7) 1.42 (0.70–2.89) 1.03 (0.40–2.66)
 ≥25 909 (37.8) 5121 (32.7) 2.35 (2.03–2.71) 2.40 (2.07–2.79) 15 (25.4) 894 (38.2) 1* 1
Sex
 Female 829 (34.5) 7273 (46.4) 1* 1 27 (45.8) 802 (34.2) 1 1
 Male 1573 (65.5) 8386 (53.6) 1.65 (1.50–1.80) 1.58 (1.43–1.73) 32 (54.2) 1,541 (65.8) 0.62 (0.37–1.04) 0.67 (0.38–1.14)
Seasonal variation
 Dry season (Jan–Apr) 367 (15.3) 2897 (18.5) 1* 1 25 (42.4) 733 (31.3) 1 1
 Rainy season (May–Sep) 1261 (52.5) 8483 (54.2) 1.17 (1.04–1.33) 1.17 (1.03–1.33) 21 (35.6) 990 (42.3) 0.62 (0.35–1.12) 0.69 (0.32–1.51)
 Cold season (Oct–Dec) 774 (32.2) 4279 (27.3) 1.43 (1.25–1.63) 1.20 (1.04–1.38) 13 (22.0) 620 (26.4) 0.62 (0.31–1.21) 0.54 (0.28–1.02)
Transportation conditionsa
 Good 692 (28.8) 9675 (61.8) 1* 1 20 (33.9) 922 (39.4) 1 1
 Poor 1710 (71.2) 5984 (38.2) 4.0 (3.64–4.39) 4.28 (4.25–5.31) 39 (66.1) 1,421 (60.6) 1.27 (0.73–2.18) 0.74 (0.18–1.62)
Parasite species
 P. falciparum 54 (91.5) 1,999 (85.3) 1.86 (0.74–4.68) 1.86 (0.73–4.75)
 P. vivax 5 (8.5) 344 (14.7) 1 1

For analysis between severe and non-severe cases, uncomplicated cases or non-severe cases were considered as referent group; aThe transportation was grouped according to the roads condition regardless of the distance between patient’s place and township hospital: good: can go easily by any vehicles in all seasons, poor: the route consumed prolonged time or have to take both vehicles and foot even near or far; *p-value < 0.05 as determined by chi-square test; COR Crude odds ratio, AOR Adjusted odds ratio, CI Confidence Interval