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. 2022 Jul 19;13(8):1345–1350. doi: 10.1021/acsmedchemlett.2c00260

Table 1. Inhibitory Activity of Nirmatrelvir and Its Analogs against SARS-CoV-2 and HCoV 229E Arranged Based on Increasing Molecular Weightsa.

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a

Warheads are depicted in red. Asterisks represent potentially reactive electrophilic carbons.