Skip to main content
. 2022 Jul 23;27(15):4723. doi: 10.3390/molecules27154723

Scheme 12.

Scheme 12

Three-component synthesis and anticancer evaluation of 3H-pyrazolo[4,3-f]quinoline derivatives 116 and 117. Reaction conditions: (a) (i) EtOH, reflux, 2 h, and (ii) cyclic ketone 44, catalyst HCl, reflux, 12 h; (b) (i) THF, reflux, 2 h, and (ii) acyclic ketone or acetophenone 44 and I2 (10 mol%), reflux, 12 h.