Table 4.
Compound | R | Yield 21 (%) | SA | EF | BS | |||
---|---|---|---|---|---|---|---|---|
CPM (mm) | MIC (μg/L) | CPM (mm) | MIC (μg/L) | CPM (mm) | MIC (μg/L) | |||
21a | 2,4-diClC6H3 | 78 | 13 | 32 | 14 | 32 | 12 | 32 |
21b | C6H5 | 62 | 15 | 32 | 13 | 16 | 15 | 16 |
21c | 4-ClC6H4 | 50 | 13 | 32 | 24 | 32 | 16 | 32 |
21d | 4-MeC6H4 | 62 | 16 | 32 | 16 | 32 | 18 | 32 |
21e | 3-MeC6H4 | 66 | 19 | 16 | 15 | 32 | 14 | 64 |
21f | 4-BrC6H4 | 71 | 14 | 32 | 13 | 64 | 15 | 32 |
21g | 3-BrC6H4 | 70 | 14 | 32 | 15 | 32 | 16 | 32 |
21h | 4-NO2C6H4 | 52 | 12 | 64 | 14 | 32 | 16 | 32 |
21i | 3-NO2C6H4 | 63 | 14 | 32 | 12 | 64 | 17 | 32 |
21j | 4-MeOC6H4 | 64 | 10 | 64 | 13 | 32 | 10 | 32 |
21k | 4-FC6H4 | 57 | 13 | 32 | 13 | 32 | 20 | 8 |
21l | 4-CF3C6H4 | 76 | 16 | 16 | 16 | 32 | 16 | 32 |
21m | 2,6-diClC6H3 | 40 | 15 | 32 | 13 | 32 | 12 | 32 |
21n | 2-Naphthyl | 76 | 14 | 32 | 13 | 32 | 15 | 32 |
21o | 2-Thienyl | 75 | 13 | 32 | 20 | 32 | 15 | 16 |
Ciprofloxacin a | -- | -- | 27 | ≤0.25 | 24 | ≤0.25 | 25 | ≤0.25 |
a Positive control for the study. SA (Staphylococcus aureus), EF (Enterococcus faecalis), BS (Bacillus subtilis).