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. 2022 Jul 23;27(15):4723. doi: 10.3390/molecules27154723

Table 42.

Antifungal activity of 4-[(3-aryl-1-phenyl-1H-pyrazol-4-yl)methylidene]-2,4-dihydro-3H-pyrazol-3-ones 34.

graphic file with name molecules-27-04723-i066.jpg
Compound R Zone of Inhibition (mm)
Aspergillus niger Sclerotium rolfsii
34a C6H5 9.8 12.8
34b 4-FC6H4 8.2 10.2
34c 4-ClC6H4 6.9 12.0
34d 4-BrC6H4 7.7 9.8
34e 4-MeC6H4 8.0 10.2
34f 4-MeOC6H4 7.8 8.5
34g 3-MeOC6H4 6.8 9.0
34h 4-OHC6H4 6.9 11.3
34i 4-NO2C6H4 7.9 10.8
34j 2,4-(Cl)2C6H3 8.9 13.2
Ketoconazole a -- 18.3 22.1

a Standard drug for the study.