Table 2.
Associations between rs61955196 and schizophrenia based on multiple models, n (%)1
|
Model
|
Genotype
|
SCZ (%)
|
HC (%)
|
OR (95%CI)
|
P
value
|
AIC
|
BIC
|
| Codominant | CC | 157 (35.4) | 202 (39.5) | 1.00 | 1279.8 | 1299.2 | |
| GC | 213 (48.1) | 244 (47.8) | 1.16 (0.88-1.55) | 0.297 | |||
| GG | 73 (16.5) | 65 (12.7) | 1.54 (1.03-2.30) | 0.037a | |||
| Dominant | CC | 157 (35.4) | 202 (39.5) | 1.00 | 0.120 | 1279.7 | 1294.3 |
| GC + GG | 286 (64.6) | 309 (60.5) | 1.24 (0.95-1.62) | ||||
| Recessive | CC + GC | 370 (83.5) | 446 (87.3) | 1.00 | 0.068 | 1278.9 | 1293.5 |
| GG | 73 (16.5) | 65 (12.7) | 1.41 (0.97-2.04) | ||||
| Overdominant | CC + GG | 230 (51.9) | 267 (52.2) | 1.00 | 0.810 | 1282.1 | 1296.7 |
| GC | 213 (48.1) | 244 (47.8) | 1.03 (0.80-1.34) | ||||
| Log-additive | - | - | - | 1.22 (1.01-1.48) | 0.040a | 1278 | 1292.6 |
a
P < 0.05.
1
Adjusted for gender.
SCZ: Schizophrenia; HC: Healthy control; OR: Odds ratio; AIC: Akaike information criterion; BIC: Bayesian information criterion.