Table 3.
Association analysis for famine and single-nucleotide polymorphisms, n (%)1
|
Group
|
SNP
|
Genotype
|
Famine
|
Non-famine
|
P
value
|
OR
(95%CI)
|
| SCZ | rs11917047 | AA + GA | 204 (92.7) | 198 (88.8) | 0.150 | 1.00 |
| (Recessive) | GG | 16 (7.3) | 25 (11.2) | 1.62 (0.84-3.13) | ||
| rs2239681 | AA + GA | 185 (84.1) | 182 (81.6) | 0.550 | 1.00 | |
| (Recessive) | GG | 35 (15.9) | 41 (18.4) | 1.16 (0.71-1.91) | ||
| rs3842756 | CC | 198 (90) | 207 (92.8) | 0.270 | 1.00 | |
| (Codominant) | CT | 22 (10) | 16 (7.2) | 0.68 (0.35-1.34) | ||
| rs61955196 | CC + GG | 117 (53.2) | 113 (50.7) | 0.610 | 1.00 | |
| (Overdominant) | GC | 103 (46.8) | 110 (49.3) | 1.10 (0.76-1.60) | ||
| HC | rs11917047 | AA + GA | 249 (91.5) | 210 (87.9) | 0.160 | 1.00 |
| (Recessive) | GG | 23 (8.5) | 29 (12.1) | 1.50 (0.84-2.68) | ||
| rs2239681 | AA + GA | 222 (81.6) | 187 (78.2) | 0.330 | 1.00 | |
| (Recessive) | GG | 50 (18.4) | 52 (21.8) | 1.24 (0.80-1.92) | ||
| rs3842756 | CC | 257 (94.5) | 218 (91.2) | 0.150 | 1.00 | |
| (Codominant) | CT | 15 (5.5) | 21 (8.8) | 1.65 (0.83-3.27) | ||
| rs61955196 | CC + GG | 144 (52.9) | 123 (51.5) | 0.750 | 1.00 | |
| (Overdominant) | GC | 128 (47.1) | 116 (48.5) | 1.06 (0.75-1.50) |
1
Adjusted for gender.
SCZ: Schizophrenia; HC: Healthy control; OR: Odds ratio; SNP: Single-nucleotide polymorphism.