Table 8.
Interactions between select antifungal drugs and essential oils against S. cerevisiae (AR0399). Colors based on interpretation. Green: synergistic; yellow: additive or indifferent; red: antagonistic.
| Antifungal | Essential Oil | FICAF | FICEO | FICI | Interpretation |
|---|---|---|---|---|---|
| Micafungin | Cinnamon Bark | 1 | 1 | 2 | Indifferent |
| Micafungin | Clove Bud | 0.5 | 0.5 | 1 | Additive |
| Micafungin | Lemongrass | 0.25 | 0.125 | 0.375 | Synergistic |
| Flucytosine | Cinnamon Bark | 1 | 0.75 | 1.75 | Indifferent |
| Flucytosine | Clove Bud | 0.25 | 0.5 | 0.75 | Additive |
| Flucytosine | Lemongrass | 0.5 | 0.5 | 1 | Additive |
| Amphotericin B | Cinnamon Bark | 1 | 0.5 | 1.5 | Indifferent |
| Amphotericin B | Clove Bud | 4 | 1 | 5 | Antagonistic |
| Amphotericin B | Lemongrass | 0.25 | 0.5 | 0.75 | Additive |
| Fluconazole | Cinnamon Bark | 1 | 0.5 | 1.5 | Indifferent |
| Fluconazole | Clove Bud | 0.25 | 0.25 | 0.5 | Synergistic |
| Fluconazole | Lemongrass | 0.125 | 0.5 | 0.625 | Additive |