Figure 2.
Effects of Bifidobacterium infantis and programmed cell death ligand inhibition on the proportion of CD4+, CD25+, and forkhead box protein 3+ cells in the blood. A: The strategy of CD4+, CD25+, and forkhead box protein (Foxp) 3+ cells; B-F: Flow cytometry results for the control group (B), the DSS model group (C), the DSS + B. infantis group (D), the DSS + B. infantis + anti-PD-L1 group (E), the DSS + anti-PD-L1 group (F); G: Statistical chart of the numbers of CD4+, CD25+, and Foxp3+ cells. Data are presented as mean ± SD, and the comparisons among each group were analyzed by one-way analysis of variance. Statistical significance was set as P < 0.05. PD-1: Programmed cell death 1; PD-L1: Programmed cell death ligand; DSS: Dextran sulfate sodium; B. infantis: Bifidobacterium infantis; Foxp3+: Forkhead box protein 3+; CD: Cluster of differentiation; SSC: Side scatter; FSC: Forward scatter; FL: Fluorescence; APC: Allophycocyanin; FITC: Fluorescein isothiocyanate; H: Height.