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. 2022 Jul 25;14(15):3613. doi: 10.3390/cancers14153613

Figure 4.

Figure 4

API treatment decreased miR-155 expression in OPC mice, which correlated with increased SHIP-1 expression. Relative (A) miR-155 and (B) SHIP-1 gene expression in the BM of CTRL, OPC and OPC-API mice. (C,D) WB analysis and representative quantification of SHIP-1 protein in the BM of CTRL, OPC and OPC-API mice. (E) Relative miR-155 gene expression in the pancreas or tumor of CTRL, OPC and OPC-API mice. Data are presented as the mean ± S.D. of CTRL (n = 3), OPC (n = 3–4), OPC-API (n = 3–4) mice. * p < 0.05; ** p < 0.001; **** p < 0.0001 (by two-tailed t test).