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API treatment decreased miR-155 expression in KC-HPC mice, which correlated with an increase in SHIP-1 expression. Relative (A) miR-155 and (B) SHIP-1 gene expression in the tumors from KC-HPC and KC-HPC-API mice. (C,D) WB analysis and representative quantification of SHIP-1 protein from the tumors of KC-HPC and KC-HPC-API mice. Data are presented as the mean ± S.D. of KC-HPC (n = 3–4), KC-HPC-API (n = 3–4). * p < 0.05; ** p < 0.01 (by two-tailed t test).
