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. 2022 Jul 25;14(15):3613. doi: 10.3390/cancers14153613

Figure 7.

Figure 7

API treatment of KC-HPC mice modulated MDSC and macrophage subsets in the BM. Flow cytometric analysis and representative quantification of (A,B) MDSC subsets, G-MDSC (CD11b+Ly6C+/−Ly6G+) and M-MDSC (CD11b+Ly6G−Ly6C+), and (C,D) macrophage subsets, M1 (CD11b+Ly6C+/−Ly6G−F4/80+CD206−MHCII+) and M2 (CD11b+Ly6C+/−Ly6G−F4/80+CD206+MHCII−), from the BM of CTRL, KC-HPC and KC-HPC-API treated mice. Data are presented as the mean ± S.D. of CTRL (n = 3–4), KC-HPC (n = 4) and KC-HPC-API (n = 3–4) mice. * p < 0.05; ** p < 0.01; *** p < 0.001 (by two-tailed t test).