Table 4.
Comparison of characteristics between participants with physical normality or decline in all the participants
| Variables | Oldest-old women | Centenarian women | All | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Physical declinea (N = 117) | Physical normalitya (N = 351) | P | Physical declinea (N = 560) | Physical normalitya (N = 198) | P | Physical declinea (N = 677) | Physical normalitya (N = 549) | P | |
| Age (year)b | 87.0 (83.0, 91.0) | 84.0 (82.0, 88.0) | < 0.001 | 102.0 (101.0, 104.0) | 102.0 (101.0, 104.0) | 0.637 | 102.0 (100.0, 104.0) | 88.0 (83.0, 101.0) | < 0.001 |
| Han ethnicity, n (%)c | 97 (82.9) | 317 (90.3) | 0.030 | 494 (88.2) | 178 (89.9) | 0.521 | 591 (87.3) | 495 (90.2) | 0.117 |
| Illiteracy, n (%)c | 107 (91.5) | 325 (92.6) | 0.689 | 543 (97.0) | 189 (95.5) | 0.316 | 650 (96.0) | 514 (93.6) | 0.058 |
| Smoker, n (%)c | 4 (3.4) | 9 (2.6) | 0.871 | 37 (6.6) | 15 (7.6) | 0.643 | 41 (6.1) | 24 (4.4) | 0.191 |
| Drinker, n (%)c | 22 (18.8) | 58 (16.5) | 0.571 | 78 (13.9) | 25 (12.6) | 0.646 | 100 (14.8) | 83 (15.1) | 0.865 |
| E2 (pmol/L)b | 18.4 (18.4, 36.9) | 18.4 (18.4, 36.9) | 0.276 | 36.9 (18.4, 61.5) | 18.5 (18.4, 38.7) | < 0.001 | 34.0 (18.4, 55.5) | 18.4 (18.4, 36.9) | < 0.001 |
| T (nmol/L)b | 0.4 (0.2, 0.9) | 0.4 (0.2, 0.9) | 0.973 | 0.4 (0.2, 0.8) | 0.3 (0.2, 0.6) | 0.001 | 0.4 (0.2, 0.8) | 0.4 (0.2, 0.8) | 0.168 |
| E2/Tb | 59.4 (25.7, 172.2) | 55.8 (23.0, 141.5) | 0.620 | 94.5 (48.4, 204.4) | 102.2 (51.5, 204.4) | 0.894 | 86.3 (42.7, 204.4) | 68.1 (31.2, 184.2) | < 0.001 |
| FSH (mIU/mL)b | 83.1 (69.1, 103.2) | 82.3 (64.0, 98.6) | 0.122 | 82.3 (62.2, 102.2) | 78.3 (59.2, 96.2) | 0.035 | 82.3 (63.4, 102.3) | 82.3 (61.8, 97.3) | 0.084 |
| LH (mIU/mL)b | 38.1 (30.2, 46.2) | 35.5 (27.5, 41.6) | 0.002 | 37.5 (29.4, 47.8) | 33.7 (26.2, 43.1) | 0.001 | 37.5 (29.6, 47.6) | 34.9 (26.9, 42.3) | < 0.001 |
| ADLb | 85 (70, 90) | 100 (100, 100) | < 0.001 | 75 (50, 85) | 95 (95, 100) | < 0.001 | 75.0 (55, 85) | 100.0 (95, 100) | < 0.001 |
ADL activity of daily living; E2 estradiol; E2/T estradiol/testosterone; FSH follicle-stimulating hormone; LH luteinizing hormone; T testosterone
aPhysical normality was defined by a total score of ADL ≥ 95 points, and physical decline was defined by a total score of ADL < 95 points
bContinuous variables with skewed distributions were presented with medians (interquartile ranges) and compared with Mann–Whitney U tests
cCategorical variables were presented with numbers (percentages) and compared with Chi-square tests