Table 6.
Multivariate logistic regression analyses with physical normalitya in all the participants
| Models | Variables | Oldest-old women | Centenarian women | All | |||
|---|---|---|---|---|---|---|---|
| Odds ratio (95% confidence interval) | P | Odds ratio (95% confidence interval) | P | Odds ratio (95% confidence interval) | P | ||
| Model 1b | E2 (pmol/L)e | 1.00 (0.98, 1.02) | 0.782 | 0.98 (0.97, 0.99) | < 0.001 | 0.97 (0.97, 0.98) | < 0.001 |
| T (nmol/L)e | 1.00 (0.88, 1.14) | 0.990 | 0.90 (0.78, 1.04) | 0.158 | 1.02 (0.95, 1.11) | 0.557 | |
| E2/Te | 1.00 (1.00, 1.00) | 0.996 | 1.00 (1.00, 1.00) | 0.881 | 1.00 (1.00, 1.00) | 0.487 | |
| FSH (mIU/mL)e | 1.00 (0.99, 1.01) | 0.826 | 1.00 (0.99, 1.01) | 0.487 | 1.00 (0.99, 1.00) | 0.649 | |
| LH (mIU/mL)e | 0.98 (0.96, 1.01) | 0.136 | 0.98 (0.96, 1.00) | 0.062 | 0.98 (0.97, 1.00) | 0.006 | |
| Model 2c | E2 (pmol/L)e | 1.00 (0.98, 1.02) | 0.937 | 0.98 (0.97, 0.99) | < 0.001 | 0.97 (0.97, 0.98) | < 0.001 |
| T (nmol/L)e | 0.98 (0.85, 1.12) | 0.756 | 0.90 (0.78, 1.04) | 0.168 | 1.03 (0.95, 1.11) | 0.529 | |
| E2/Te | 1.00 (1.00, 1.00) | 0.837 | 1.00 (1.00, 1.00) | 0.846 | 1.00 (1.00, 1.00) | 0.509 | |
| FSH (mIU/mL)e | 1.00 (0.99, 1.01) | 0.831 | 1.00 (0.99, 1.01) | 0.455 | 1.00 (0.99, 1.01) | 0.635 | |
| LH (mIU/mL)e | 0.99 (0.96, 1.01) | 0.185 | 0.98 (0.96, 1.00) | 0.066 | 0.98 (0.97, 1.00) | 0.006 | |
| Model 3d | E2 (pmol/L)e | 1.00 (0.98, 1.02) | 0.996 | 0.98 (0.97, 0.99) | < 0.001 | 0.98 (0.98, 0.99) | < 0.001 |
| T (nmol/L)e | 0.99 (0.86, 1.13) | 0.865 | 0.91 (0.79, 1.05) | 0.180 | 0.99 (0.92, 1.08) | 0.887 | |
| E2/Te | 1.00 (1.00, 1.00) | 0.929 | 1.00 (1.00, 1.00) | 0.835 | 1.00 (1.00, 1.00) | 0.824 | |
| FSH (mIU/mL)e | 1.00 (0.99, 1.01) | 0.823 | 1.00 (0.99, 1.01) | 0.479 | 1.00 (0.99, 1.00) | 0.448 | |
| LH (mIU/mL)e | 0.99 (0.97, 1.01) | 0.267 | 0.98 (0.96, 1.00) | 0.060 | 0.99 (0.97, 1.00) | 0.031 | |
E2 estradiol; E2/T estradiol/testosterone; FSH follicle-stimulating hormone; LH luteinizing hormone; T testosterone
aPhysical normality was defined by a total score of ADL ≥ 95 points, and physical decline was defined by a total score of ADL < 95 points
bMultivariate logistic regression analyses were used with E2, T, E2/T, FSH and LH as independent variables and with physical normality/decline as dependent variable
cMultivariate logistic regression analyses were used with ethnicity, education, smoker, drinker, E2, T, E2/T, FSH and LH as independent variables and with physical normality/decline as dependent variable
dMultivariate logistic regression analyses were used with age, ethnicity, education, smoker, drinker, E2, T, E2/T, FSH and LH as independent variables and with physical normality/decline as dependent variable
ePer 1 unit increase