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. 2022 Summer;40(3):327–338. doi: 10.2337/cd21-0104

TABLE 4.

Participant Characteristics by MRI Liver Steatosis Grade

Variable Median (IQR) or n (%)
≤5% Steatosis (n = 23) 5–33% Steatosis (n = 64) 34–66% Steatosis (n = 19) >66% Steatosis (n = 14)
Age, years 63 (61–67.24) 61.16 (56.80–65.64) 64.36 (55.16–68.27) 59.07 (50.61–61.85)
Sex
Male
Female

18 (78.3)
5 (21.70)

36 (56.3)
28 (43.8)

13 (68.4)
6 (31.6)

7 (50)
7 (50)
Duration of diabetes, years 12 (6–19) 10 (5–17) 8 (3–10) 8 (1.75–10.5)
BMI, kg/m2 26.6 (25–30.80) 30.9 (27.87–34.77) 31 (28.75–32) 33 (29.24–38.65)
Waist circumference, cm
Male
Female

95 (90–109.25)
95 (82.5–103)

109.5 (98–115.5)
102 (96–107–25)

111 (103–121)
97 (96–100.25)

120 (108–127)
103 (100–104)
Systolic blood pressure, mmHg 120 (110–130) 130 (120–130) 125 (120–130) 120 (120–130)
Diastolic blood pressure, mmHg 65 (60–70) 60 (60–70) 60 (60–80) 60 (58.75–70)
A1C, % 6.6 (6.20–7.23) 6.6 (6.2–7.3) 6.8 (6.3–7.3) 6.79 (6.24–6.93)
Glucose, mg/dL 122 (108.75–147.75) 121 (102.5–142.75) 127 (106–144) 128 (107.75–143.75)
AST, units/L 17 (14–20) 18 (15–23) 20 (16–23) 31 (21.75–40)
ALT, units/L 14.5 (12–19.25) 20 (17–29) 24 (19–38) 48.5 (32.5–70.75)
TSH, mg/dL 1.57 (1.09–18.6) 1.41 (10.7–2.19) 1.2 (0.8–1.99) 2 (1.12–2.77)
Total cholesterol, mg/dL 147.5 (129.25–167.75) 157 (136.25–174.5) 153 (132–169) 177.5 (126–189.5)
HDL cholesterol, mg/dL
Male
Female

48 (37–53.75)
65 (50–75.5)

41.5 (35.2–49)
51 (43.2–57.5)

40 (35–49.5)
43 (38.75–55)

41 (35–46)
44 (39–50)
LDL cholesterol, mg/dL 85 (71–97) 90.5 (76.5–108) 82 (62–94) 91.5 (63.5–114.25)
VLDL cholesterol, mg/dL 21 (15–33) 24 (18–32.75) 24 (17–48) 32.5 (19.7–41.5)
Triglycerides, mg/dL 106 (74–127) 116 (92.5–161.75) 109 (97–193) 141 (117.75–218)
 SteatoTest grade
S0
S0–S1
S1
S1–S2
S2
S2–S3
S3

8 (40)
6 (30)
2 (10)
1 (5)
2 (10)
0 (0)
0 (0)

14 (22.2)
3 (4.8)
12 (19)
14 (22.2)
9 (14.3)
3 (4.8)
8 (12.7)

2 (10.5)
4 (21.1)
2 (10.5)
4 (21.1)
2 (10.5)
1 (5.3)
4 (21.1)

1 (7.1)
0 (0)
0 (0)
5 (35.7)
1 (7.1)
1 (7.1)
6 (42.9)
NashTest 2 grade
N0
N1
N2
N3

8 (44.4)
5(27.8)
5 (27.8)
0 (0)

9 (15.5)
29 (50)
18 (31)
2 (3.4)

2 (11.8)
9 (52.9)
5 (29.4)
1 (5.9)

0 (0)
5 (38.5)
5 (38.5)
3 (23.1)
ActiTest grade
A0
A1
A2
A3

18 (78.3)
2 (8.7)
0 (0)
0 (0)

53 (84.1)
8 (12.7)
0 (0)
2 (3.2)

14 (73.7)
5 (26.3)
0 (0)
0 (0)

4 (28.6)
9 (64.3)
1 (7.1)
0 (0)
FibroTest stage
F0
F0–F1
F1
F1–F2
F2
F3
F3–F4
F4

5 (25)
5 (25)
2 (10)
8 (40)
0 (0)
0 (0)
0 (0)
0 (0)

29 (46)
7 (11.1)
2 (3.2)
13 (20.6)
3 (4.8)
6 (9.5)
2 (3.2)
1 (1.6)

7 (36.8)
2 (10.5)
3 (15.8)
3 (15.8)
0 (0)
3 (15.8)
0 (0)
1 (5.3)

7 (50)
1 (7.1)
2 (14.3)
1 (7.1)
1 (7.1)
2 (14.3)
0 (0)
0 (0)