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The integrated intensity profile of S. agalactiae protein-lysate-loaded HNTs exposed to 0.3% bile salt solution for 7 h. H, HA, HC and HAC represent the protein-releasing profiles of HNT, HNT-APTES, HNT-Chitosan and HNT-APTES-Chitosan, respectively. Statistical analysis was performed via a paired two-sample t-test: for an analysis of means with p < 0.05. “*” indicates a significant difference between unmodified (H) and other modified HNTs (HA, HC and HAC) at each time point.
