Figure 3.

Effect of metformin treatment on hepatic steatosis index (HSI) in non-obese, obese and very obese patients. The HSI was assessed in subgroups of non-obese (BMI < 30 kg/m²), obese (BMI 30-35 kg/m²) and very obese (BMI > 35 kg/m²) women with PCOS before (t(0)) and after (t(1)) treatment with metformin. Differences between the HSI at t(1) vs. t(0) were tested using Wilcoxon tests for paired non-parametric analyses. Data are presented as mean ± standard error of the mean. *** p < 0.001. HSI: hepatic steatosis index.