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. 2022 Jul 14;12:940706. doi: 10.3389/fonc.2022.940706

Figure 4.

Figure 4

MPO was significantly correlated with the infiltration level of neutrophils in CRC. (A) MPO expression has a significant correlation with many immune cells infiltration. (B, C) The correlation between MPO and neutrophils by the Wilcoxon signed-rank and Spearman correlation tests. (D) We analyzed the correlation between MPO expression and T cells, B cells, CD8+ T cells, cytotoxic cells, DC, macrophages, mast cells, neutrophils, NK cells, Th1 cells, Th17 cells, Th2 cells, and Tregs using ssGSEA. (E) The relationship between different immune cells and MPO was analyzed in TIMER 2.0, including B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils, and DCs. (F–H) The relationship between MPO and neutrophils in a single-cell RNA sequencing database. The difference was considered significant at * P < 0.05, ** P < 0.01, or *** P < 0.001. ns, no significance.