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. 2022 Jul 14;12:940706. doi: 10.3389/fonc.2022.940706

Figure 5.

Figure 5

MPO was upregulated in CRC and positively correlated with peripheral neutrophil counts. (A) IHC was used to detect MPO protein expression in CRC and non-cancerous tissues (69 pairs); left, scale bar = 250 µm; right, scale bar = 50 µm. (B) Quantitative analysis of MPO IHC scores in CRC and non-cancerous tissues (69 pairs). (C) qPCR was used to evaluate the relative expression of MPO mRNA in CRC and adjacent non-cancerous tissues (69 pairs). (D) The relationship between MPO levels in CRC and peripheral neutrophil counts was determined using Spearman’s correlation test (r = 0.406, P < 0.001, n = 69). Differences were considered significant at * P < 0.05, ** P < 0.01, or *** P < 0.001.