Table 3.
Univariate analysis of prognostic factors for OS with the Cox regression model.
| Characteristics | Total (N) | Univariate analysis HR (95% CI) | Univariate analysis P value |
|---|---|---|---|
| T stage (T3&T4 vs. T1&T2) | 476 | 3.072 (1.423-6.631) | 0.004 |
| N stage (N1&N2 vs. N0) | 477 | 2.592 (1.743-3.855) | <0.001 |
| M stage (M1 vs. M0) | 414 | 4.193 (2.683-6.554) | <0.001 |
| Pathological stage (Stage III&Stage IV vs. Stage I&Stage II) | 466 | 2.947 (1.942-4.471) | <0.001 |
| TP53 (High vs. Low) | 477 | 0.819 (0.555-1.208) | 0.313 |
| Sex (Male vs. Female) | 477 | 1.101 (0.746-1.625) | 0.627 |
| Age (>65 vs. <=65) | 477 | 1.610 (1.052-2.463) | 0.028 |
| BMI (>=25 vs. <25) | 256 | 0.549 (0.311-0.969) | 0.038 |
| Residual tumor (R1&R2 vs. R0) | 373 | 4.364 (2.401-7.930) | <0.001 |
| CEA level (>5 vs. <=5) | 302 | 3.128 (1.788-5.471) | <0.001 |
| Perineural invasion (YES vs. NO) | 181 | 1.940 (0.982-3.832) | 0.056 |
| Lymphatic invasion (YES vs. NO) | 433 | 2.450 (1.614-3.720) | <0.001 |
| History of colon polyps (YES vs. NO) | 407 | 0.741 (0.442-1.242) | 0.255 |
| Colon polyps present (YES vs. NO) | 249 | 1.324 (0.738-2.373) | 0.346 |
| MPO (High vs. Low) | 477 | 1.618 (1.087-2.407) | 0.018 |