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. 2022 Jul 14;13:880286. doi: 10.3389/fimmu.2022.880286
EMPs erythro-myeloid progenitors
PB peripheral blood
iPSC induced pluripotent stem cell
ICs immune complexes
ROS reactive oxygen species
Arg1 arginase 1
MIP macrophages inflammatory protein
RANTES regulated on
activation normal T cell expressed and secreted
MCP-1 monocyte chemo-attractant protein-1
iNOS inducible nitric oxide synthase
TNF tumor necrosis factor
TLR toll-like receptor
TGF‐b transforming growth factor‐b
LPS lipopolysaccharide
GM-CSF granulocyte-macrophage colony stimulating factor
VEGF vascular endothelial growth factor
ERK extracellular signal-regulated kinase
EGF epidermal growth factor
IRF interferon‐regulatory factors
AMPK adenosine monophosphate kinase
AP1 activator protein1
NF‐kB nuclear factor‐kB
PPAR‐g peroxisome proliferator‐activated receptor‐g
SIRPa signal regulatory protein a
Tim-3 T cell immunoglobulin and mucin domain-3
PK pyruvate kinase
HK2 hexokinase 2
PPP pentose phosphate pathway
PFK1 phosphofructokinase 1
G6PD Glucose 6-phosphate dehydrogenase
OXPHOS oxidative phosphorylation
IDH isocitrate dehydrogenase
NADPH nicotinamide-adenine dinucleotide phosphate
SDH succinate dehydrogenase
ACLY ATP‐citrate lyase
ETC electron transport chain
IL-1b interleukin-1b
IRG1 immuneresponsive gene 1
HIF-1a hypoxia inducible factor 1a
PPR proton production rate
LDHA lactate dehydrogenase A
FAO fatty acid oxidation
FAS fatty acid synthesis
FASN fatty acid synthase
PDPK1 phosphoinositol-dependent protein kinase 1
LDs lipid droplets
NRF2 Nuclear Factor Erythroid 2-Related Factor 2
PUFA polyunsaturated fatty acid
a-KG aketoglutarate
TAMs tumor-associated macrophages
ABCA1 ATP-binding cassette transporter A1
IR insulin resistance
CPT carnitine palmitoyltransferase
AT adipose tissue
FC free cholesterol
ATMs adipose tissue-derived macrophages