EMPs |
erythro-myeloid progenitors |
PB |
peripheral blood |
iPSC |
induced pluripotent stem cell |
ICs |
immune complexes |
ROS |
reactive oxygen species |
Arg1 |
arginase 1 |
MIP |
macrophages inflammatory protein |
RANTES |
regulated on |
activation |
normal T cell expressed and secreted |
MCP-1 |
monocyte chemo-attractant protein-1 |
iNOS |
inducible nitric oxide synthase |
TNF |
tumor necrosis factor |
TLR |
toll-like receptor |
TGF‐b |
transforming growth factor‐b |
LPS |
lipopolysaccharide |
GM-CSF |
granulocyte-macrophage colony stimulating factor |
VEGF |
vascular endothelial growth factor |
ERK |
extracellular signal-regulated kinase |
EGF |
epidermal growth factor |
IRF |
interferon‐regulatory factors |
AMPK |
adenosine monophosphate kinase |
AP1 |
activator protein1 |
NF‐kB |
nuclear factor‐kB |
PPAR‐g |
peroxisome proliferator‐activated receptor‐g |
SIRPa |
signal regulatory protein a |
Tim-3 |
T cell immunoglobulin and mucin domain-3 |
PK |
pyruvate kinase |
HK2 |
hexokinase 2 |
PPP |
pentose phosphate pathway |
PFK1 |
phosphofructokinase 1 |
G6PD |
Glucose 6-phosphate dehydrogenase |
OXPHOS |
oxidative phosphorylation |
IDH |
isocitrate dehydrogenase |
NADPH |
nicotinamide-adenine dinucleotide phosphate |
SDH |
succinate dehydrogenase |
ACLY |
ATP‐citrate lyase |
ETC |
electron transport chain |
IL-1b |
interleukin-1b |
IRG1 |
immuneresponsive gene 1 |
HIF-1a |
hypoxia inducible factor 1a |
PPR |
proton production rate |
LDHA |
lactate dehydrogenase A |
FAO |
fatty acid oxidation |
FAS |
fatty acid synthesis |
FASN |
fatty acid synthase |
PDPK1 |
phosphoinositol-dependent protein kinase 1 |
LDs |
lipid droplets |
NRF2 |
Nuclear Factor Erythroid 2-Related Factor 2 |
PUFA |
polyunsaturated fatty acid |
a-KG |
aketoglutarate |
TAMs |
tumor-associated macrophages |
ABCA1 |
ATP-binding cassette transporter A1 |
IR |
insulin resistance |
CPT |
carnitine palmitoyltransferase |
AT |
adipose tissue |
FC |
free cholesterol |
ATMs |
adipose tissue-derived macrophages |