AMPK |
AMP kinase |
Atg5 |
Autophagy-related 5 protein |
BBB |
Blood–brain barrier |
CNS |
Central nervous system |
CSF |
Cerebrospinal fluid |
EAE |
Experimental autoimmune encephalomyelitis |
DDIT4 |
DNA damage-inducible transcript 4 |
FKBP12 |
FK506-binding protein of 12 kDa |
GCs |
Glucocorticoids |
Gd |
Gadolinium |
iPSCs |
Induced pluripotent stem cells |
LPS |
Lipopolysaccharide |
MS |
Multiple sclerosis |
mTOR |
Mammalian target of rapamycin |
mTORC1 |
mTOR complex 1 |
mTORC2 |
mTOR complex 2 |
NLRP3 |
NOD-like receptor protein 3 |
NO |
Nitric oxide |
NPCs |
Neural progenitor cells |
OLs |
Mature oligodendrocytes |
Pi3K-AKT |
Phosphoinositide-3-kinase/protein kinase B |
PPMS |
Primary progressive MS |
ROS |
Reactive oxygen species |
RRMS |
Relapsing–remitting MS |
SGK1 |
Serum- and glucocorticoid-induced protein kinase 1 |
SPMS |
Secondary progressive MS |
TCR |
T cell receptor |
Tregs |
Regulatory T cells |
TSC |
Tuberous sclerosis complex |