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A representative list of mTOR inhibitors.
| Inhibitor | Category of mTOR Inhibitor | Inhibition Effect |
|---|---|---|
| Rapamycin (AY-22989) | Rapamycin | Direct mTOR inhibition |
| Temsirolimus (CCI-779) | Rapalogs | |
| Everolimus (RAD-001) | ||
| Ridaforolimus (AP23573) | ||
| OSI-027 | TORC1/TORC2 inhibitors | |
| Vistusertib (AZD2014) | ||
| AZD8055 | ||
| Dactolisib (BEZ235) | PI3K/mTOR inhibitors | Indirect mTOR inhibition |
| Apitolisib (GDC-0980) | ||
| Gedatolisib (PF05212384) | ||
| Omipalisib (GSK2126458) | ||
| Metformin (A10BA02) | AMPK activation |
