Table 1.

Some of the most widely used rodent models of HD and temporal course of motor alterations.

	Mouse Models						Rat Model
HTT gene	Fragment		Full-length		Knock-in	mHTT minus N17	Fragment
Line	R6/2	R6/1	YAC128	BACHD	Q175 (Het)	BACHD ΔN17	tgHD
Number of CAGs	~155	~110	~128	97	~175	97	51
Hyperactivity	✓ (3 weeks)	✓ (4 weeks)	✓ (3 months)	—	—	—	✓ (6 months)
Motor deficits	✓ (>5 weeks)	✓ (3 months)	✓ (9 months)	✓ (>2 months)	✓ (>4 months)	✓ (>2 months)	✓ (>10 months)
Chorea	—	—	—	—	—	✓ (>7 months)	✓ (17 months)