Table 6.
Glutathione determination in blood of participants “Baseline” and “6 months” stratified by adherence to Mediterranean diet (AMD).
| Under Median Value (<50%) | Above Median Value (≥50%) | ANOVA | |||||
|---|---|---|---|---|---|---|---|
| Baseline (n = 31) | 6 Months (n = 31) | Baseline (n = 36) | 6 Months (n = 36) | AMD | T | AMD × T | |
| Mean ± SEM | Mean ± SEM | Mean ± SEM | Mean ± SEM | ||||
| tGSH (mM/L blood) | 3.27 ± 0.35 | 4.33 ± 0.28 | 3.27 ± 0.21 | 4.99 ± 0.25 # | 0.237 | <0.001 | 0.224 |
| GSSG (mM/L blood) | 0.345 ± 0.011 | 0.370 ± 0.011 | 0.342 ± 0.012 | 0.386 ± 0.014 | 0.585 | 0.007 | 0.457 |
| tGSH/GSSG | 9.81 ± 1.24 | 10.1 ± 0.78 | 11.9 ± 0.83 | 13.7 ± 0.96 # | 0.279 | 0.003 | 0.409 |
Abbreviations: tGSH, total glutathione; GSSG, oxidized glutathione; tGSH/GSSG, ratio of total glutathione and oxidized glutathione. Results are expressed as mean ± SEM. Statistics by two-way ANOVA: AMD effect of adherence to the Mediterranean diet, T effect of time, AMD × T interaction between adherence to the Mediterranean diet and time. # Difference in means between time. Each variable was adjusted by baseline values of the analyzed variable.