Table 7.
Under Median Value (<50%) | Above Median Value (≥50%) | ANOVA | |||||
---|---|---|---|---|---|---|---|
Baseline (n = 31) | 6 Months (n = 31) | Baseline (n = 36) | 6 Months (n = 36) | AMD | T | AMD × T | |
Mean ± SEM | Mean ± SEM | Mean ± SEM | Mean ± SEM | ||||
Immunoassays | |||||||
MPO (ng/mL) | 3.87 ± 0.32 | 3.22 ± 0.20 | 4.57 ± 2.58 | 3.26 ± 0.15 # | 0.153 | <0.001 | 0.201 |
Resolvin D1 (pg/mL) | 133.7 ± 4.5 | 156.6 ± 6.1 # | 145.6 ± 3.82 | 162.7 ± 4.01 # | 0.055 | 0.000 | 0.527 |
Irisin (ng/mL) | 108.6 ± 10.0 | 98.3 ± 10.3 | 127.4 ± 11.6 | 109.3 ± 9.2 | 0.156 | 0.177 | 0.708 |
CK-18 (U/L) | 60.5 ± 5.3 | 47.7 ± 5.3 | 78.2 ± 6.0 | 48.2 ± 2.9 # | 0.073 | <0.001 | 0.089 |
IL-6 (pg/mL) | 4.27 ± 0.05 | 4.18 ± 0.05 | 4.31 ± 0.03 | 4.20 ±0.3 # | 0.410 | 0.013 | 0.723 |
TNFα (pg(mL) | 4.10 ± 0.20 | 4.03 ± 0.18 | 4.02 ± 0.07 | 3.93 ± 0.07 | 0.484 | 0.548 | 0.938 |
Abbreviations: MPO, myeloperoxidase; CK-18, cytokeratin 18; XOD, xanthine oxidase; IL-6, interleukin-6; TFNα, tumor necrosis factor alpha. Results are expressed as mean ± SEM. Statistics by two-way ANOVA: AMD effect of adherence to the Mediterranean diet, T effect of time, AMD × T interaction between adherence to the Mediterranean diet and time. # Difference in means between time. Each variable was adjusted by baseline values of the analyzed variable.