Table 1.

Clinical presentation of Case 1 (TUBB2B mutation) and Case 2 (TUBA1A mutation).

	Case 1	Case 2
Gender, age	Male, 23 years	Male, 1 years 2 months
Age of seizure onset	1 h	4 h
Consanguinity	no	no
Prenatal history	malformation of brain	unremarkable
Epilepsy	multifocal, refractory	focal to generalized, recurrent
Hypotonia	yes	yes
Developmental delay	global	global
Skeletal involvement	scoliosis	unknown
Feeding	gastrostomy	oral
Mutation	TUBB2B	TUBA1A