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. 2022 Jul 25;11(15):4322. doi: 10.3390/jcm11154322

Table 3.

CPET data in the three groups of patients.

Data ICU Group
n = 31
MLC Group
n = 23
Adjusted
p Value (Comparison between ICU Group and LC Group)
OB Group
n = 15
Adjusted
p Value (Comparison between ICU Group and OB Group)
Kruskal–Wallis Test
p Value
Maximum predicted VO2 (mL/min/kg) 24.8 [19.7–28] 26.2 [23.7–33.4] NS 22.3 [15.5–25.5] NS 0.048
HR (bpm) 159 [152–167] 176 [170–183] <0.001 168 [151–190] NS 0.001
Workload (W) 155.5 [131–172] 136 [128–182] NS 135 [103–185] NS NS
πO2 (mL/beat) 15.8 [10.8–17.1] 10.3 [9.1–15.2] NS 14.5 [11.7–18.8] NS 0.036
Resting state HR (bpm) 77 [66–87] 76 [66–86] NS 91 [74–99] NS 0.051
Systolic blood pressure (mmHg) 140 [130–145] 120 [110–120] <0.001 125 [117–130] NS <0.001
Diastolic blood pressure (mmHg) 70 [70–70] 60 [60–70] 0.03 80 [70–85] NS 0.004
VO2 (mL/min/kg) 8 [5.6–9.7] 6.1 [4.4–7.6] NS 4.4 [3.3–5.2] <0.001 0.001
MET 2.4 [1.8–3.1] 1.7 [1.3–2.3] NS 1.3 [0.9–1.5] <0.001 <0.001
RER 0.85 [0.8–0.91] 0.77 [0.73–0.82] 0.001 0.8 [0.76–0.84] NS 0.002
πO2 (mL/beat) 7.7 [6.2–13.2] 5.5 [4.8–6.1] 0.028 4.1 [3.3–5.2] <0.001 <0.001
Veq CO2 29.6 [26.2–34.4] 35.9 [31.3–40.1] 0.004 32.3 [30.4–34.5] NS 0.005
ADT VO2 (% peak) 66 [57–74] 52 [48–59] <0.001
AT VO2 (% peak) 81 [72.5–87.2] 85 [75–91] NS 44.5 [34.5–58.3] <0.001 <0.001
Peak Workload (% max predicted) 66 [40.9–79.2] 104.4 [95.6–122.3] <0.001 94.7 [77.7–123.9] 0.003 <0.001
VO2 (% max predicted) 74.5 [62.6–102.8] 105.3 [86.8–132.8] 0.005 74 [62–84.3] NS <0.001
HR (% max predicted) 76.7 [65.1–90.3] 97.9 [88.7–101.1] <0.001 80.6 [74–89.3] NS <0.001
πO2 (% max predicted) 109 [75.5–135.4] 116 [105–134] NS 72.9 [56.4–85.4] 0.002 <0.001
Veq CO2 29.5 [26.6–34.4] 33 [30.4–40.9] NS 31.5 [29.6–34.3] NS 0.117
VE (l/min) 61.1 [44.7–72.8] 79.4 [64.4–89.5] 0.007 60 [40–71] NS 0.004
VE/VCO2 slope 33.6 [29.1–44.9] 26 [22.9–34.9] NS 32.1 [29.5–33.5] NS 0.066
CR (%) 57.8 [35.5–79.3] 96.5 [73.2–101.7] <0.001 59.5 [43.1–71.7] NS <0.001
BR (%) 33 [19.8–41.5] 19.1 [6.6–31.2] NS 48 [30–58] NS 0.001
T1/2 VO2 (% peak) 51 [49.2–53] 50 [49–51] NS 49.4 [45.2–52.4] NS 0.212
HR (% peak) 79.2 [75–85] 69.2 [64.6–74.2] <0.001 78.7 [76.4–90.4] NS <0.001
RER 1.13 [1–1.2] 0.97 [0.91–1.03] 0.021 1.38 [1.29–1.45] <0.001 <0.001
πO2 (% peak) 62.4 [56.2–69.9] 47.6 [42.2–53.8] <0.001 59.7 [54.8–68.2] NS <0.001
Veq CO2 (% peak) 107.4 [100.2–117.4] 133.1 [121.7–144.7] <0.001 107.8 [102.9–114.5] NS <0.001

Data are expressed as the median with lower and upper quartiles [Q1–Q3] or count (%). NS: non-significant.