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. 2022 Jul 26;27(15):4779. doi: 10.3390/molecules27154779

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Metabolic pathways related to catechol biosynthesis in E. coli. Arrows with dashed lines indicate more than one enzymatic reaction. Abbreviations: ANT, anthranilate; AntAB, terminal oxygenase component; AntC, reductase component of anthranilate 1,2-dioxygenase; DAHP, 3-deoxy-d-arabino-heptulosonate-7-phosphate; DHQ, 3-dehydroquinicacid; DHS, 3-dehydroshikimicacid; E4P, erythrose-4-phosphate; PCA, protocatechuate; PEP, phosphoenolpyruvate; SA, shikimic acid; Genes and coded enzymes: aroB, DHQ synthase; aroD, DHQ dehydratase; aroE, shikimate dehydrogenase; aroF, DAHP synthase; aroG^fbr, feedback inhibition resistant DAHP synthase; ECL, PCA decarboxylase; trpED, anthranilate synthase-phosphoribosyl transferase complex.