Table 3.
Demographic characteristics, comorbid conditions, and death from COVID-19 of patients hospitalized for SARS-CoV-2, stratifying by admission to intensive care unit (ICU) and waves.
| First Wave (1 March–15 April 2020) |
Second Wave (15 October–15 December 2020) |
Third Wave (1 March–15 April 2021) |
|||||
|---|---|---|---|---|---|---|---|
| No ICU N/Day a (%) |
ICU N/Day a (%) |
No ICU N/Day a (%) |
ICU N/Day a (%) |
No ICU N/Day a (%) |
ICU N/Day a (%) |
p-Value b | |
| Age group | |||||||
| ≤65 | 38.3 (32.8%) | 19.4 (43.2%) ***,c | 47.8 (29.0%) | 17.8 (33.2%) ***,d | 47.2 (34.2%) | 18.2 (41.2%) ***,e | <0.001 |
| 66–75 | 22.5 (18.8%) | 13.3 (29.7%) | 31.2 (18.9%) | 16.8 (31.2%) | 32.5 (23.6%) | 15.2 (34.5%) | |
| 76–85 | 36.0 (30.0%) | 9.8 (21.9%) | 51.9 (31.5%) | 15.0 (27.9%) | 39.0 (28.3%) | 8.8 (20.0%) | |
| 86+ | 22.1 (18.4%) | 2.3 (5.2%) | 33.9 (20.6%) | 4.1 (7.7%) | 19.2 (13.9%) | 1.9 (4.3%) | |
| Gender | |||||||
| F | 52.9 (44.1%) | 13.2 (29.4%) ***,c | 72.4 (43.9%) | 17.0 (31.6%) ***,d | 60.7 (44.0%) | 15.8 (35.9%) ***,e | <0.001 |
| M | 67.0 (55.9%) | 31.7 (70.6%) | 92.5 (56.1%) | 36.7 (68.4%) | 77.2 (56.0%) | 28.3 (64.1%) | |
| Charlson Comorbidity Index | |||||||
| 0 | 56.6 (47.2%) | 23.1 (51.4%) **,c | 76.9 (46.6%) | 25.0 (46.5%) *,d | 71.9 (52.1%) | 24.0 (54.5%) **,e | <0.001 |
| 1 | 32.1 (26.8%) | 12.0 (26.7%) | 45.7 (27.7%) | 16.0 (29.8%) | 36.5 (26.5%) | 12.2 (27.6%) | |
| 2–3 | 23.0 (19.2%) | 7.4 (16.4%) | 31.6 (19.2%) | 9.7 (18.1%) | 23.1 (16.8%) | 6.3 (14.2%) | |
| 4+ | 8.2 (6.8%) | 2.5 (2.5%) | 10.7 (6.5%) | 3.0 (5.6%) | 6.4 (4.6%) | 1.6 (3.7%) | |
| Death | |||||||
| No | 87.3 (72.8%) | 28.7 (64.0%) ***,c | 128.0 (77.6%) | 36.0 (67.0%) ***,d | 115.2 (83.5%) | 31.8 (72.2%) ***,e | <0.001 |
| Yes | 32.5 (27.2%) | 16.1 (36.0%) | 36.9 (22.4%) | 17.7 (33.0%) | 22.7 (16.5%) | 12.3 (27.8%) | |
a N/day average number of cases per day; b Comparisons of patients admitted to ICU among the three waves tested by Chi-square or Fisher test; c Comparison between patients admitted in ICU and in other wards (No ICU) during the first wave tested by Chi-square or Fisher test; d Comparison between patients admitted in ICU and in other wards (No ICU) during the second wave tested by Chi-square or Fisher test; e Comparison between patients admitted in ICU and in other wards (No ICU) during the third wave tested by Chi-square or Fisher test; *** p < 0.001; ** p < 0.01; * p < 0.05.