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. 2022 Jul 25;11(15):4304. doi: 10.3390/jcm11154304

Table 5.

Demographic characteristics, comorbid conditions, and intensive care unit (ICU) admission of hospitalized for SARS-CoV-2, stratifying by death within 30 days from the first positive swab and waves.

First Wave
(1 March–15 April 2020)
Second Wave
(15 October–15 December 2020)
Third Wave
(1 March–15 April 2021)
No Death
N/Day a (%)
Death
N/Day a (%)
No Death
N/Day a (%)
Death
N/Day a (%)
No Death
N/Day a (%)
Death
N/Day a (%)
p-Value b
Age group
≤65 54.2 (46.7%) 4.4 (9.1%) ***,c 61.3 (37.4%) 4.2 (7.8%) ***,d 61.5 (41.9%) 3.8 (10.8%) ***,e <0.001
66–75 26.6 (22.9%) 9.3 (19.1%) 39.2 (23.9%) 8.8 (16.2%) 39.6 (26.9%) 8.1 (23.2%)
76–85 25.3 (21.9%) 20.5 (42.0%) 44.2 (26.9%) 22.8 (41.7%) 34.2 (23.3%) 13.6 (38.8%)
86+ 9.9 (8.5%) 14.5 (29.8%) 19.3 (11.8%) 18.8 (34.3%) 11.6 (7.9%) 9.5 (27.2%)
Gender
F 47.8 (41.2%) 18.3 (37.6%) **,c 68.1 (41.5%) 21.2 (38.8%) **,d 62.7 (42.7%) 13.8 (39.3%) *,e 0.49
M 68.3 (58.8%) 30.4 (62.4%) 95.8 (58.5%) 33.4 (61.2%) 84.3 (57.3%) 21.2 (60.7%)
Charlson Comorbidity Index
0 63.2 (54.5%) 16.4 (33.7%) ***,c 82.9 (50.5%) 19.0 (34.7%) ***,d 82.1 (55.8%) 13.8 (39.4%) ***,e 0.006
1 29.6 (25.5%) 14.5 (29.8%) 45.9 (28.0%) 15.7 (28.8%) 38.6 (26.3%) 10.0 (28.7%)
2–3 17.9 (15.4%) 12.4 (25.6%) 27.3 (16.7%) 14.0 (25.7%) 21.4 (14.6%) 8.0 (22.9%)
4+ 5.3 (4.6%) 5.3 (10.9%) 7.9 (4.8%) 5.9 (10.8%) 4.9 (3.3%) 3.1 (8.9%)
ICU admission
No 87.3 (75.2%) 32.5 (66.9%) ***,c 128.0 (78.0%) 36.9 (67.6%) ***,d 115.2 (78.4%) 22.7 (65.0%) ***,e 0.18
Yes 28.7 (24.8%) 16.1 (33.1%) 36.0 (22.0%) 17.7 (32.4%) 31.8 (21.6%) 12.3 (35.0%)

a N/day average number of cases per day; b Comparisons of dead patients among the three waves tested by Chi-square or Fisher test; c Comparison between alive and dead patients during the first wave tested by Chi-square or Fisher test; d Comparison between alive and dead patients during the second wave tested by Chi-square or Fisher test; e Comparison between alive and dead patients during the third wave tested by Chi-square or Fisher test; *** p < 0.001; ** p < 0.01; * p < 0.05.