Table 3.
Inhibition of collagenase and elastase.
| EOs | Anti-collagenase activity | Anti-elastase activity | ||
|---|---|---|---|---|
|
|
|
|||
| IC50 (μg/mL) | Inhibition % at 400 μg/mL | IC50 (μg/mL) | Inhibition % at 800 μg/mL | |
| CH | 28.71 ± 0.16 | 72.10 ± 0.24 | 412.76 ± 2.77 | 63.21 ± 0.16 |
| CR | 153.73 ± 0.24 | 64.09 ± 2.02 | 302.75 ± 1.56 | 61.23 ± 0.33 |
| CGp | 132.67 ± 0.15 | 61.55 ± 0.29 | 13052 ± 1.59 | 42.43 ± 0.43 |
| PA | 440.88 ± 0.72 | 47.00 ± 0.40 | 724.15 ± 0.97 | 49.08 ± 0.03 |
| PT | 329.22 ± 0.11 | 49.88 ± 0.86 | 1530.20 ± 22.54 | 32.23 ± 0.19 |
| CZ | 337.75 ± 0.15 | 52.82 ± 0.37 | NA | 34.63 ± 0.19 |
| Control | 24.45 ± 0.19a | 91.24 ± 0.94a | 33.7 ± 0.15b | 75.10 ± 0.20b |
Values are mean ± standard error of the mean of three assays.
CGp = Citrus grandis; CH = Citrus hystrix; CR = Citrus reticulata; CZ = Cinnamomum zeylanicum; EO = essential oil; Gal = galantamine, PA = Psiadia arguta; PT = Psiadia terebinthina.
a
Collagenase inhibitor.
b
Elastase inhibitor.