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. 2022 Jul 27;13(8):1341. doi: 10.3390/genes13081341

Table 2.

Transcriptome-wide association study (TWAS) results for PTSD.

Reference Weight Population CHR SNP Genes Z-Score p-Value
Rnaseq All 2 rs7557285 FBXO41 3.44 9.85 × 10−6
5 rs11747154 PCDHA9 −2.27 5.09 × 10−3
1 rs949571 ZBTB41 −2.11 1.54 × 10−3
1 rs34001546 C1orf54 −3.09 4.28 × 10−3
6 rs9477555 KIF13A 4.32 5.55 × 10−3
Female 16 rs2377058 CHMP1A −2.99 5.09 × 10−4
5 rs6879760 PCDHA9 −2.69 4.17 × 10−4
6 rs1049346 GLO1 2.50 1.41 × 10−3
22 rs4474965 DGCR8 3.76 2.33 × 10−3
1 rs34001546 C1orf54 −2.76 5.15 × 10−3
Male 3 rs2267846 P4HTM 2.13 1.82 × 10−43
1 rs6690515 ATAD3A −4.10 2.59 × 10−4
8 rs4876218 CLN8 3.04 5.37 × 10−4
4 rs4696175 TRIM2 −3.13 2.87 × 10−3
19 rs383547 RAB3D −2.43 6.75 × 10−3
Splicing All 7 rs7798233 AKAP9 2.51 1.51 × 10−13
7 rs741664 PLXNA4 −3.69 1.24 × 10−4
6 rs4712047 SIRT5 2.64 4.81 × 10−3
11 rs17787912 MADD −2.43 1.23 × 10−2
8 rs17817071 RIMS2 −2.64 3.84 × 10−2
Female 2 rs11681740 COL5A2 −2.21 1.69 × 10−6
5 rs891943 SLC6A7 3.63 4.47 × 10−4
11 rs4757650 LDHA −3.20 1.50 × 10−3
17 rs2010838 AMZ2 3.28 1.92 × 10−3
5 rs7700814 GLRX −3.02 2.29 × 10−3
Male 7 rs13229505 AKAP9 2.57 1.19 × 10−10
7 rs741664 PLXNA4 4.15 4.56 × 10−4
19 rs17211813 FKBP8 3.45 3.23 × 10−4
7 rs38417 GGCT 2.91 5.55 × 10−4
4 rs7375984 FSTL5 3.53 3.52 × 10−4

Abbreviations: CHR, Chromosome; SNP, Single nucleotide polymorphism; p-value, Analytical permutation p-values.