Table 3. Similar Case of Takotsubo Cardiomyopathy With High Degree AV Block, QT Prolongation, and TdP Resulting in Near Arrest (NA) or Cardiac Arrest (CA) Within 24 - 48 h of Hospital Admission.
Article | Age/sex | Past medical history | ECG rhythm on admission | Duration of QT interval on admission ECG | TTE findings | Timing of NA or CA | Rhythm causing NA or CA | Temporality of TTE findings with TdP and/or CA | Timing of PPP |
---|---|---|---|---|---|---|---|---|---|
Ahn et al, 2011 [27] | 78/F | HTN | Third-degree HB with EJR of 35 b/min, combined with TWI precordial leads | 580 ms | Akinesia of mid and apical LV walls with the systolic ballooning of the ventricular apex; LVEF: 35% | 24 - 48 h | Third-degree HB with EJR of 20 b/min QTc 720 ms followed by TdP (treated by CV and TVP) | Before | Day 21 |
de Santana et al, 2021 [24] | 56/F | HTN, grade 2 obesity | Second degree AVB 2:1 with EJR of 50 b/min, RBBB, LAFB, biphasic and inverted T waves in precordial and limb leads | 689 ms | Basal hypercontractility and midventricular and apical ballooning. LVEF: 40% | 24 h | VF (treated by CV and TVP) | Before | Day 14 |
Inayat et al, 2017 [8] | 59/F | None | Third-degree AVB with EJ VR 48 b/min, multiple PVCs, prolonged, and deep TWI in limb leads | 643 ms | Basal hyperkinesia and apical hypokinesis with LVEF of 35-40% | 24 - 48 h | TdP (treated medically and TVP) | Before | Day 6 |
Kurisu et al, 2008 [26] | 87/F | Syncope | RBBB during 2:1 AVB with a VR of 42 b/min, TWI in leads I, II, aVL, aVF and V1 to V6 | 880 ms | Akinesia of the distal portion of the LV chamber, LVEF 62% | Immediately | TdP (treated medically and TVP) | After | Day 10 |
Kurisu et al, 2008 [26] | 78/F | Not reported | RBBB during complete AVB with a VR of 40 b/min, ST segment elevation in leads V2 to V6, T wave inversion in leads I, II, III, aVF and V1 to V6 | 920 ms | Akinesia of the mid to distal portion of the LV chamber, LVEF 38% | Immediately | TdP (treated medically and TVP) | After | Day 7 |
ECG: electrocardiogram; VF: ventricular fibrillation; CV: cardioversion; EJR: escape junctional rhythm; HB: heart block; RBBB: right bundle branch block; AVB: atrioventricular block; TWI: T wave inversion; VR: ventricular rate; PVC: premature ventricular contractions; TdP: torsade de pointes; TTE: transthoracic echocardiogram; b/min: beats/min; HTN: hypertension; TVP: temporary venous pacing; PPP: permeant pacemaker placement; LAFB: left anterior fascicular block; LVEF: left ventricular ejection fraction.