Table 2.
Clinical and Genetic Prognostic Factors
Univariate Analysis | Multivariate Analysis | |||
---|---|---|---|---|
Prognostic Factor | HR (95% CI) | P value | HR (95% CI) | P value |
Sex (male) | 1.60 (0.93-2.75) | .093 | 1.60 (0.91-2.83) | .104 |
Age (>70 years) | 2.53 (1.47-4.33) | <.001* | 2.72 (1.51-4.92) | <.001* |
KPS score (≤80 points) | 1.46 (0.81-2.64) | .210 | 1.76 (0.92-3.37) | .088 |
PTR/biopsy | 2.05 (1.20-3.48) | .008* | 1.85 (1.03-3.32) | .041* |
Unmethylated MGMTp | 2.10 (1.24-3.57) | .006* | 3.00 (1.67-5.39) | <.001* |
PDGFRA gain/amp | 2.22 (1.30-3.78) | .003* | 1.82 (1.00-3.31) | .049* |
KPS, Karnofsky Performance Status; PTR, partial tumor removal.
The symbol * indicates statistical significance.