Table IV.
Associations of factors with sub-groups of BA
| Characteristic | Adjusted PR (95%CI)* | ||
|---|---|---|---|
| Sub-group 1: Isolated BA (n=212) | Sub-group 2: BA with non-laterality birth defects (n=66) | Sub-group 3: BA with laterality defects (n=27) | |
| Infant sex | |||
| Male | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) |
| Female | 1.76 (1.33–2.32) | 1.71 (1.04–2.83) | 1.14 (0.54–2.43) |
| Gestational Age | |||
| >37 weeks | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) |
| 32–37 weeks | 1.09 (0.68–1.73) | 3.80 (2.13–6.77) | 2.10 (0.79–5.60) |
| <32 weeks | 2.91 (1.54–5.52) | 8.63 (3.86–19.31) | 2.32 (0.31–17.33) |
| Season of conception | |||
| Spring | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) |
| Summer | 0.70 (0.48–1.02) | 1.12 (0.57–2.22) | 0.86 (0.36–2.07) |
| Fall | 0.66 (0.45–0.97) | 0.81 (0.39–1.69) | 0.09 (0.01–0.70) |
| Winter | 0.84 (0.59–1.19) | 1.16 (0.60–2.25) | 0.53 (0.20–1.43) |
| Maternal race/ethnicity | |||
| NH White | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) |
| NH Black | 1.39 (0.88–2.21) | 2.07 (0.94–4.58) | 1.62 (0.50–5.27) |
| Hispanic | 1.17 (0.86–1.60) | 1.60 (0.89–2.89) | 0.93 (0.39–2.21) |
| Other | 1.84 (1.01–3.33) | 2.43 (0.81–7.27) | 1.86 (0.40–8.67) |
| Maternal diabetes | |||
| No | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) |
| Yes | 2.16 (1.32–3.56) | 1.42 (0.51–3.92) | 6.83 (2.73–17.08) |
| Pre-gestational diabetes** | |||
| No | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) |
| Yes | 3.21 (1.02–10.10) | 2.71 (0.37–19.84) | 26.58 (7.51–94.04) |
| Gestational diabetes** | |||
| No | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) |
| Yes | 1.14 (0.50–2.58) | 1.17 (0.28–4.86) | 2.87 (0.66–12.56) |
*
In order to compare a full complement across the three sub-groups, this model adjusts for the same variables of interest regardless of significance within each individual sub-group.
**
Analysis limited to subset of patients born between 2005–2014 (n=137 in sub-group 1, n=42 in sub-group 2, and n=18 in sub-group 3).
Abbreviations: NH = Non-Hispanic; PR = Prevalence ratio; CI = Confidence interval; Ref = Reference