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The expression of miR-31 was analyzed by quantitative real-time polymerase chain reaction. Relative miR-31 expression levels were normalized to (a) miR-16, (b) miR-1228 and (c) cel-miR-39. HC: Healthy controls, BT: Before therapy of CRC patients, AT: After therapy of CRC patients, **: P < 0.01, *: P < 0.05, #: P < 0.1
