Table 1.

Gene loci associated with uric acid measurement and/ or gout: Data derived from genome-wide association study catalog

Phenotype/disease	Protein-coding gene loci
Uric acid measurement only	A1CF, ALDH3B1, ANKRD33-FIGNL2-DT, ARHGAP26, B4GALT1, BANF1-CST6, BAZ1B, BCAS1, BICC1, BRAP, C11orf80, C1QTNF9B-ANKRD20A19P, CARMIL1, CCDC18, CNTN4, COMMD4-ANP32BP1, CPS1, CYB5B-NFAT5, DACH1, DCDC2, DIP2C-AL157709.1, DNAH3, DPEP1, EIF1AD, ETV5, F5, FAT4-ANKRD50, FLRT1-MACROD1, FRAS1, FRMD8, GAD1, GAREM1, GNAS, GPLD1, HECTD4, HLA-DQA1-HLA-DQB1, HLF, HNF4A, HNF4G, IGF1R, INHBC, INSR, IPO11-ISCA1P1, KCNE1, KIAA0319, KLHL5, RNU1-130P, LMAN2-MXD3, LRP2, MAFTRR, MAJIN, MALAT1, MAP4K2, MAPKAPK5-ADAM1A, MARK4-EXOC3L2, METTL6, MPPED2-AS1, MTCYBP37, MUC1, MYO9A, MYOF, NDUFAF6, NFATC2, NFKB1, NR5A2, NRAD1, NRG4, NTRK1-INSRR, ORC4, OVOL1, PACS1, PCNX3, PIGN, PKD2, PLAAT2-PLAAT4, PLAAT5, PNPLA3, POLA2, PPP2R5B, PSORS1C1-PSORS1C2, PYGM, QRICH2, RAI14, RBM14-RBM4, RGS20, RN7SKP182, RNASEH2C-KRT8P26, RNF115, RNU1-148P-STC1, RPH 3A, RPL21P41, RPL32P31, RPL7P45, RPS6KA4, RREB1-AL139390.1, RSPO3, RTN4RL1-RPA1, SBF2, SELENOO, SESN2, SESTD1, SHF, SHROOM3, SIPA1L3, SLC10A2, SLC14A2, SLC17A3, SLC17A4, SLC22A10, SLC22A24, SLC25A26-LRIG1, SLC27A5, SLC29A2, STK32B, SYN3, TENM2, TM4SF4, TMC6, TMEM171, TMEM18, TSGA10IP-DRAP1, TSHR, TTLL1, UMOD, UNCX, USP2, USP34, VEGFA, VPS37D-MLXIPL, VPS45, VPS51, WDR1, WDR72, WNT7A, ZBTB4, ZNF318, ZNF584
Gout only	AADACL2-AS1, ABCA1, ABCC8, ABCC9, ABCG1, AC002463.1, RBFOX1, ZNF724, RN7SKP93, CLDN24, ACSM2B, H4C5, AL157886.1, OR13C8, ALDH1A2, ALX4, LINC02724, ARID5B, ASB10, ATP1A4, BDKRB2, CFTR, CNIH2, CNPY4, CNTN5, CYB5AP4, CYP2C8, CYP2E1, DST, EIF3IP1, EVA1A, FAM53A, FGFR2, FSTL4, FTH1P22, GABPA, GLUD1, GRID1, HGF, JAZF1, LHFPL3, LMCD1-AS1, MALRD1, MRPS36P2, MSC-AS1, NIPAL1, NSUN3-ARMC10P1, NTNG2-MED27, PDE1C, PIBF1, POLD3, PPARD, PPARGC1A-DHX15, PRKAG2, PRKCA, PTPRD, PXDNL, RARB, RFX3-AS1, RUNX2-CLIC5, SLC13A3, SLC22A1, SLC22A18AS, SLC38A1, SMARCC1, SMYD3, SV2B, TPST1, VDR, WNT5B
Both uric acid measurement and gout	ABCG2, BCAS3, RN7SL496P, CACNA2D3, SFMBT1, ZMYM6, ACAD10, THEM4, TRIM46, ALDH2, ANO2, BAIAP2, CCDC75P1, CDC42BPG-MEN1, CUX2, FAAHP1, PRDM8-FGF5, GCKR-C2orf16, GREM2, KCNQ1, MYL2, MAP3K11, MAPK6, MLXIP, MRPS33P3-RPF2P2, MYH11, NAA25, NALCN, NRXN2, OR4D5-OR8D4, OR6M1-OR6M2P, CD160-PDZK1, PKNOX2, RAB27B, SHLD2, SLC16A9, SLC17A1, SLC22A11-SLC22A12, SLC2A9, SNX18P26-CYP4F34P, WWOX