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. 2022 Jul 28;17(7):e0271431. doi: 10.1371/journal.pone.0271431

Table 3. Predictors of HIV infection (prevalence) in participants aged 15–59 years by sex, Lesotho Population-based HIV Impact Assessment 2016–2017*.

Men Women
Odds Ratio (OR) (95% Confidence Interval [CI]) p-value Adjusted Odds Ratio (aOR) (95% CI) p-value OR (95% CI) p-value aOR (95% CI) p-value
Per additional year of age (15–49) 1.32 (1.27–1.37) <0.001 1.29 (1.23–1.35) <0.001 1.26 (1.23–1.29) <0.001 1.22 (1.19–1.26) <0.001
Area of Residence
 Urban Ref. --- Ref. --- Ref. --- Ref. ---
 Rural 0·94 (0·81–1·11) 0·46 0·63 (0·47–0·83) 0·002 0·94 (0·84–1·05) 0.24 0.83 (0.70–0.98) 0·026
Ecological Zone
 Lowlands Ref. --- Ref. --- Ref. --- Ref. ---
 Foothills 0.97 (0.75–1.26) 0.84 0.95 (0.66–1.36) 0.751 0.86 (0.72–1.04) 0.115 0.79 (0.62–1.01) 0.055
 Mountains 1.00 (0.84–1.19) 0.999 0.70 (0.54–0.91) 0.010 0.90 (0.79–1.04) 0.151 0.73 (0.60–0.88) 0.002
Wealth Quintile (per one unit increase) 0.89 (0.84–0.94) <0.001 0.91 (0.81–1.03) 0.004 0.95 (0.92–0.98) 0.003 0.89 (0.83–0.96) <0.001
Years of Schooling
Per additional educational level attended 0.88 (0.60–0.90) <0.001 0.95 (0.66–1.36) 0.002 0.88 (0.86–0.90) <0.001 0.91 (0.89–0.94) <0.001
Marital Status
 Married/living Together Ref. --- Ref. --- Ref. --- Ref. ---
 Single 0·19 (0·15–0.23) <0·001 0.63 (0.48–0.84) <0·001 0.49 (0.43–0.56) <0·001 1.32 (1.09–1.61) 0.007
 Divorced/Sep./Widowed 2·47 (1·96–3·11) <0·001 2.05 (1.59–2.66) <0·001 3·18 (2.77–3.66) <0·001 2.41 (2.06–2.83) <0·001
Lived Outside of Lesotho
 Never Ref. --- Ref. --- Ref. --- Ref. ---
 Once 1·74 (1·41–2·14) <0·001 1.06 (0.83–1.34) 0.65 1.58 (1·35–1·85) <0·001 1.18 (0.98–1.43) 0.08
 Twice 1.75 (1.22–2.50) 0.004 1.00 (0.66–1.53) 0.98 2.06 (1.42–2.99) <0.001 1.43 (0.96–2.12) 0.07
 Three or More 1.91 (1.49–2.45) <0.001 1.05 (0.81–1.36) 0.72 1.49 (1.16–1.91) <0.001 1.02 (0.77–1.37) 0.88
Age at First Sex
 Younger than 15 years 0·56 (0·44–0·72) <0·001 1.03 (0.77–1.39) 0.73 1.44 (1.17–1.92) 0.019 1.36 (1.00–1.86) 0.05
 Older than 15 years 1.59 (1.15–2.19) 0.007 0.93 (0.59–1.45) 0.84 1.61 (1.15–2.27) 0.008 1.08 (0.68–1.74) 0.730
Use of Condom at First Sex
 No Ref. --- Ref. --- Ref. --- Ref. ---
 Yes 0.29 (0.24–0.36) <0.001 0.73 (0.57–0.93) 0.01 0.43 (0.38–0.49) <0.001 0.70 (0.59–0.83) <0.001
Overall Number of Partners
 1 Ref. --- Ref. --- Ref. --- Ref. ---
 2 1.09 (0.70–1.72) 0.68 1.22 (0.75–2.00) 0.41 1.85 (1.56–2.21) <0.001 1.79 (1.50–2.15) <0.001
 3 1.19 (0.79–1.78) 0.39 1.21 (0.79–1.87) 0.36 2.59 (2.21–3.03) <0.001 2.40 (2.04–2.83) <0.001
 4 2.00 (1.28–2.89) 0.001 1.59 (1.08–2.32) 0.02 3.68 (3.09–4.40) <0.001 3.10 (2.53–3.80) <0.001
 5 1.55 (1.08–2.22) 0.019 1.88 (1.22–2.90) 0.006 0.89 (0.72–1.09) 0.24 2.43 (1.78–3.36) <0.001
Male Circumcision
 Traditional/Uncircumcised Ref. --- Ref. --- --- ---- --- ---
 Medical Circumcision 0.36 (0.30–0.43) <0.001 0.55 (0.44–0.70) <0.001 --- --- --- ---

*Data are survey weighted. Multivariable models constructed using variable chosen a priori looking at known risk factors for HIV from relevant published literature.