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. 2022 Jul 28;17(7):e0264053. doi: 10.1371/journal.pone.0264053

Table 4. Major and minor complications, readmissions, reoperations and discharge status in 193 patients undergoing 213 keyhole operations for meningioma.

Major Surgical Complications (n = 23 patients) 25
  Permanent Neurological Worsening 12(6%)
    • Stroke 4(2%)
    • New or Worsening Cranial Nerve Dysfunction 8 (4%)
  Transient Neurological Worsening 1(0.5%)
    • Persistent seizures with transient hemiparesis 1
  Reoperations 10(5%)
    • Delayed hematoma evacuation 2
    • Reoperation for residual tumor (same admission) 2
    • Reoperation for residual tumor (readmission) 1
    • CSF leak repair 2
    • Revision of sellar reconstruction (no CSF leak) 2
    • Epistaxis needing surgical intervention 1
  Meningitis 2 (1%)
  Total Major Complications by Operation (p = 0.45)
    • Redo-operation 7/47 (15%)
    • First-time operation 18/166 (11%)
Minor Complications
    • Sinusitis 3
    • Mucocele 1
    • Forehead numbness 11
    • Frontalis paresis 7
    • Frontalis palsy 2
    • Delayed wound dehiscence 1
    • Hardware malposition 1
Systemic Complications 2 (1%)
    • Aspiration Pneumonia 1
    • UTI 1
    • DVT/PE/ MI 0
Delayed Radiation Induced Optic Neuropathy 1
Discharge to Home 201/213 (94%)
Readmissions Requiring Surgical Intervention (n = 4/213) 2%
    • Residual tumor needing more surgery 1
    • Delayed hematoma needing surgery 1
    • CSF leak repair
    • Epistaxis 1
Readmissions Managed Medically (n = 2/213) 1%
    • UTI, Atrial fibrillation
    • Hyponatremia 1

* One patient had both CSF leak and meningitis; one patient who had stroke had a multiply recurrent meningioma with prior surgery and RT and was the only mortality in the series