Table 2. |.
Biological Processes in Gene Ontology enriched by genes targeted by 11 candidate proteins (genes)
| Biological processes | Gene Ratio | Background Ratio | P | Targets |
|---|---|---|---|---|
| Neuron Differentiation | 6/11 | 137/819 | 4.4E-3 | ROR1/KLK8/DLL1/RTN4R/NRX1B/MATN2 |
| Neurogenesis | 6/11 | 158/819 | 9.3E-3 | ROR1/KLK8/DLL1/RTN4R/NRX1B/MATN2 |
| Regulation of nervous system development | 5/11 | 90/819 | 3.9E-3 | ROR1/KLK8/DLL1/RTN4R/NRX1B |
| Axon development | 4/11 | 68/819 | 9.2E-3 | KLK8/RTN4R/NRX1B/MATN2 |
| Neuron projection regeneration | 3/11 | 16/819 | 9.2E-4 | KLK8/RTN4R/MATN2 |
| Negative regulation of neuron differentiation | 3/11 | 21/819 | 2.1E-3 | KLK8/DLL1/RTN4R |
| Response to axon injury | 3/11 | 21/819 | 2.1E-3 | KLK8/RTN4R/MATN2 |
| Organic acid binding | 3/11 | 32/819 | 7.2E-3 | LAYN/FABP3/RTN4R |
| Negative regulation of nervous system development | 3/11 | 33/819 | 7.9E-3 | KLK8/DLL1/RTN4R |
| Presynapse | 3/11 | 33/819 | 7.9E-3 | ROR1/RTN4R/NRX1B |
Biological processes enriched with at least 3 candidate proteins and P < 1.0×10−2 are presented in the table.
ESAM, MAPK11, and endostatin did not enrich any biological processes in the GO database.